Dengue Fever in Thailand

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Gaybutton
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Dengue Fever in Thailand

Post by Gaybutton »

We are currently in Dengue Fever season in Thailand and there has been a huge increase in the number of cases so far this year. You need to take this seriously.

Aedes mosquitoes are visually distinctive because they have noticeable black and white markings on their bodies and legs. Unlike most other mosquitoes, they are active and bite only during the daytime. The peak biting periods are early in the morning and in the evening before dusk.

Image

Dengue symptoms usually start within a few days of being bitten but can take up to 2 weeks to develop. Symptoms can be mild or severe and can include fever with nausea, vomiting, rash, headache, eye pain, joint and muscle pain. In severe cases, dengue can cause shock, internal bleeding, and even death.

No need to be upset if you are bitten thinking that every mosquito bite will cause dengue. Only the female Aedes aegypti mosquitoes can spread the dengue virus and in fact, these mosquitoes can transfer the infection only when they themselves are infected. So, no need to panic after each mosquito bite.

Most of the cases are happening out in the boondocks provinces, but it can happen anywhere. If you start developing symptoms, seek medical attention immediately.
________________________________________

Dengue Surge Hits Provinces with 8,000+ Cases

By Goongnang Suksawat

7 February, 2024

Dengue fever has escalated into a significant concern in Thailand, with the Department of Disease Control (DDC) reporting over 8,000 infections and 13 fatalities in January.

DDC Director-General Thongchai Keeratihuttayakorn highlighted a sharp 91.25% increase in cases compared to January of the previous year, where 4,286 individuals were affected, noting as many as 8,197 people have contracted the disease so far.

Dengue fever, a viral infection spread by Aedes mosquitoes, is prevalent in tropical and subtropical regions. Symptoms include high fever, severe headaches, muscle and joint pains, nausea, vomiting, skin rashes, and swollen glands. The disease poses a higher risk to children aged five to 14, with the majority of cases reported in the southern and central parts of Thailand.

The fatalities recorded this year span across 11 provinces, with the oldest victim being 65 years old. To combat the spread, Thongchai advised that hospitals treating dengue patients provide anti-mosquito cream or spray as a preventive measure to others.

The DDC Director-General emphasized that immediate medical attention is a must for anyone experiencing fever, especially those in close proximity to diagnosed patients, to mitigate further spread and protect public health.

https://tpnnational.com/2024/02/07/deng ... 000-cases/
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Re: Dengue Fever in Thailand

Post by Daleinpattaya »

Here is a good guide for dengue.

https://www.cdc.gov/dengue/symptoms/index.html
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Re: Dengue Fever in Thailand

Post by Jun »

There's a vaccine available, but the Thai Travel Clinic DOESN'T recommend it for many people.
https://www.thaitravelclinic.com/blog/t ... et-it.html

As for catching mosquitoes, I seem to have the best success rate grabbing them with one hand.
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Re: Dengue Fever in Thailand

Post by Daleinpattaya »

Single-Dose Dengue Vaccine Provides Nearly 80% Protection

https://www.technologynetworks.com/biop ... ion-383424

A single-dose vaccine protects nearly 80% of people not previously infected with dengue.

A single-dose vaccine protects nearly 80% of people not previously infected with dengue, according to researchers from the Butantan Institute in Brazil.

Results from a Phase 3 clinical trial show that the vaccine is safe and effective for those aged 2–59 regardless of whether they have previously been infected with dengue.

Expanding dengue vaccine options

Nearly half of the world’s population live in areas where they are at risk of infection with dengue virus. Symptoms of dengue include fever, nausea, vomiting, rashes as well as aches and pains.

Most cases are mild, but around 1 in 20 of those who experience symptoms can develop potentially life-threatening “severe dengue”. Over 6 million cases of dengue were reported across 92 countries/territories in 2023 with at least 6,000 deaths.

However, there are no treatments specifically designed for the disease. Several countries have approved vaccines, but these require several doses, are approved for specific age ranges and may be recommended only for those previously exposed to the virus.

The current study, published in The New England Journal of Medicine, reports the results from a Phase 3 clinical trial of Butantan–Dengue Vaccine (Butantan-DV). This vaccine was safe and effective with a single dose and protected a wide age range regardless of previous infection.

Single dose provides protection

The study reported results from the first two years of the Phase 3 clinical trial. This involved 16,235 participants in 13 states in Brazil, where dengue is considered hyperendemic.

Endemic vs hyperendemic

A disease is classed as endemic when it is consistently present in a specific region or location. An endemic disease can become hyperendemic if it has a high incidence or prevalence.

Of these participants, 10,259 received the vaccine and 5,976 received a placebo. The vaccine was 80.1% effective for participants aged 2–6, 77.8% effective for 7–17 years and 90% effective for those aged 18–59.

Furthermore, the vaccine was 79.6% effective in those with no evidence of previous dengue infection, and 89.2% effective in those who had previous infection.
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Re: Dengue Fever in Thailand

Post by Gaybutton »

Daleinpattaya wrote: Fri Feb 09, 2024 9:50 am the vaccine is safe and effective for those aged 2–59 regardless of whether they have previously been infected with dengue.

Several countries have approved vaccines
Regarding the age constraints, my guess is few of us reading this are still under 59 years old.

Regarding countries that have approved vaccines, does anyone know if Thailand is one of those countries?
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Re: Dengue Fever in Thailand

Post by Jun »

Gaybutton wrote: Fri Feb 09, 2024 9:58 am [/sub]Regarding countries that have approved vaccines, does anyone know if Thailand is one of those countries?
An earlier post points out that The Thai Travel clinic has it available, so presumably it's approved in Thailand.
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Re: Dengue Fever in Thailand

Post by 2lz2p »

Jun wrote: Fri Feb 09, 2024 10:22 am
Gaybutton wrote: Fri Feb 09, 2024 9:58 am Regarding countries that have approved vaccines, does anyone know if Thailand is one of those countries?
An earlier post points out that The Thai Travel clinic has it available, so presumably it's approved in Thailand.
The vaccine mentioned by the Travel Clinic was available in Thailand over 5 years ago (their website mentions its availability as of 1 December 2017). If I recall correctly, the vaccine currently on offer was developed here in Thailand. Also, as I recall the publicity back then there noted there were some concerns about it, which is the reason the Travel Clinic doesn't recommend it.

The article Dale mentions is related to a new Dengue vaccine from Brazil that is still in clinical trials and not yet available. When it does become available, then it will still need Thailand's FDA approval. Extracts from the article:
A single-dose vaccine protects nearly 80% of people not previously infected with dengue.
The article mentions a higher protection rate for people who have previously been infected with Dengue (that would include me if I were much younger).
Results from a Phase 3 clinical trial show that the vaccine is safe and effective for those aged 2–59 regardless of whether they have previously been infected with dengue.
So when it does become available, the younger folks can at least benefit - as to age group, perhaps it had no one older in the Trial group(s), so maybe future trials including the elderly may find it effective without undue side effects.
The current study, published in The New England Journal of Medicine, reports the results from a Phase 3 clinical trial of Butantan–Dengue Vaccine (Butantan-DV).
“If all goes well, we’ll win definitive approval for the vaccine in 2025.
By the time they might be able to make it available for older folks, many including myself, may no longer be around to take advantage of it.
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Re: Dengue Fever in Thailand

Post by Jun »

The Thai Travel clinic has one vaccine by Sanofi and one by Takeda, ie French and Japanese companies.

Anyone seriously considering it should read why they're NOT recommending it.

As for taking a vaccine when older than the recommended age range, I wouldn't be put off for that reason. I am put off by the reasons explained in their article.

When in my 40s, I paid for HPV vaccination in the UK, despite being outside the recommended age range at the time.
If I remember correctly, gay men of up to about 50 can now get it free in the UK.
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Re: Dengue Fever in Thailand

Post by gerefan »

What’s wrong with a liberal dose of Mosquito Spray?
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Re: Dengue Fever in Thailand

Post by Jun »

gerefan wrote: Fri Feb 09, 2024 1:15 pm What’s wrong with a liberal dose of Mosquito Spray?
That does seem like a better bet than the vaccination options.
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